381 Santa Maria Ave is a house in San Luis Obispo, CA 93405. This 2,429 square foot house sits on a 5,900 square foot lot and features 4 bedrooms and 3 bathrooms. 381 Santa Maria Ave was built in 1966. Nearby schools include San Luis Obispo Classical Academy, Teach Elementary School and Manzanita School. The closest grocery stores are Campus Market, San Luis Oriental Market and Smart & Final Extra!. Nearby coffee shops include VG Cafe, Black Horse Coffee and Uptown Espresso. Nearby restaurants include Backstage Pizza, SHPE's Bacon-Wrapped Hot Dogs and Gino's Pizza. 381 Santa Maria Ave is near Buena Vista Park, Santa Rosa Park and Cheng Park. This address can also be written as 381 Santa Maria Avenue, San Luis Obispo, California 93405.